DeepFashion2 dataset raises a new challenge for a keypoint detection task. It contains 13 categories with a different number of keypoints, 294 in total. Direct prediction of all keypoints leads to huge memory consumption, slow training, and inference speed. This paper presents a study of keypoint grouping approach and how it affects performance on the example of CenterNet architecture. We propose a simple and efficient automatic grouping technique and apply it to DeepFashion2 fashion landmark task and MS COCO Human Pose task. It allows reducing memory consumption up to 30%, decreasing inference time up to 30%, and training time up to 26% without compromising accuracy.