Human Pose Estimation is a fundamental task for many applications in the Computer Vision community and it has been widely investigated in the 2D domain, i.e. intensity images. Therefore, most of the available methods for this task are mainly based on 2D Convolutional Neural Networks and huge manually-annotated RGB datasets, achieving stunning results. In this paper, we propose RefiNet, a multi-stage framework that regresses an extremely-precise 3D human pose estimation from a given 2D pose and a depth map. The framework consists of three different modules, each one specialized in a particular refinement and data representation, i.e. depth patches, 3D skeleton and point clouds. Moreover, we collect a new dataset, namely Baracca, acquired with RGB, depth and thermal cameras and specifically created for the automotive context. Experimental results confirm the quality of the refinement procedure that largely improves the human pose estimations of off-the-shelf 2D methods.