RGB-Infrared person re-identification (RGB-IR Re-ID) aims to matching persons from heterogeneous images captured by visible and thermal cameras, which is of great significance in surveillance system under poor light conditions. Facing great challenges in complex variances including conventional single-modality and additional inter-modality discrepancies, most of existing RGB-IR Re-ID methods directly work on global features for simultaneous elimination, whereas modality-specific noises and modality-shared features are not well considered. To address these issues, a novel Multi-Scale Part-Aware Cascading framework (MSPAC) is formulated by aggregating multi-scale fine-grained features from part to global in a cascading manner, which results in an unified representation robust to noises. Moreover, a marginal exponential center (MeCen) loss is introduced to jointly eliminate mixed variances, which enables to model cross-modality correlations on sharable salient features. Extensive experiments are conducted for demonstration that the proposed method outperforms all the state-of-the-arts by a large margin.