While in high demand for the development of deep learning approaches, extensive datasets of annotated UAV imagery are still scarce today. Manual annotation, however, is time-consuming and, thus, has limited the potential for creating large-scale datasets. We tackle this challenge by presenting a procedure for the automatic creation of simulated UAV image sequences in urban areas and pixel-level annotations from publicly available data sources. We synthesize photo-realistic UAV imagery from Goole Earth Studio and derive annotations from an open CityGML model that not only provides geometric but also semantic information. The first dataset we exemplarily created using our approach contains 144000 images of Berlin, Germany, with four types of annotations, namely semantic labels as well as depth, surface normals, and edge maps. In the future, a complete pipeline regarding all the technical problems will be provided, together with more accurate models to refine some of the empirical settings currently, to automatically generate a large-scale dataset with reliable ground-truth annotations over the whole city of Berlin. The dataset, as well as the source code, will be published by then. Different methods will also be facilitated to test the usability of the dataset. We believe our dataset can be used for, and not limited to, tasks like pose estimation, geo-localization, monocular depth estimation, edge detection, building/surface classification, and plane segmentation. A potential research pipeline for geo-localization based on the synthetic dataset is provided.