Accurate and robust detection objects from monocular images is a fundamental vision task. This paper describes a novel approach of holistic scene understanding that can simultaneously achieve multiple tasks of scene reconstruction and object detection from a single monocular camera. Rather than pursuing an independent solution for each individual task as most existing work does, we seek a globally optimal solution that holistically resolves the multiple perception and reasoning tasks in an effective manner. The approach explores the complementary properties of multimodal RGB imagery and depth data to improve scene perception tasks. It uniquely combines the techniques of canonical correlation analysis and deep learning to learn the most correlated features to maximize the modal cross-correlation for improving the performance and robustness of object detection in complex environments. Extensive experiments have been conducted to evaluate and demonstrate the performances of the proposed approach.