Learning to Segment Clustered Amoeboid Cells from Brightfield Microscopy Via Multi-Task Learning with Adaptive Weight Selection

Rituparna Sarkar, Suvadip Mukherjee, Elisabeth Labruyere, Jean-Christophe Olivo-Marin

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Auto-TLDR; Supervised Cell Segmentation from Microscopy Images using Multi-task Learning in a Multi-Task Learning Paradigm

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Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and intensity heterogeneity, and only a small subset are applicable to segment cells in a cluster. In this regard, we introduce a novel supervised technique for cell segmentation in a multi-task learning paradigm. A combination of a multi-task loss, based on the region and cell boundary detection, is employed for an improved prediction efficiency of the network. The learning problem is posed in a novel min-max framework which enables adaptive estimation of the hyper-parameters in an automatic fashion. The region and cell boundary predictions are combined via morphological operations and active contour model to segment individual cells. The proposed methodology is particularly suited to segment touching cells from brightfield microscopy images without manual interventions. Quantitatively, we observe an overall Dice score of 0.93 on the validation set, which is an improvement of over 15.9% on a recent unsupervised method, and outperforms the popular supervised U-net algorithm by at least 5.8% on average.

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End-To-End Multi-Task Learning for Lung Nodule Segmentation and Diagnosis

Wei Chen, Qiuli Wang, Dan Yang, Xiaohong Zhang, Chen Liu, Yucong Li

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Auto-TLDR; A novel multi-task framework for lung nodule diagnosis based on deep learning and medical features

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Computer-Aided Diagnosis (CAD) systems for lung nodule diagnosis based on deep learning have attracted much attention in recent years. However, most existing methods ignore the relationships between the segmentation and classification tasks, which leads to unstable performances. To address this problem, we propose a novel multi-task framework, which can provide lung nodule segmentation mask, malignancy prediction, and medical features for interpretable diagnosis at the same time. Our framework mainly contains two sub-network: (1) Multi-Channel Segmentation Sub-network (MSN) for lung nodule segmentation, and (2) Joint Classification Sub-network (JCN) for interpretable lung nodule diagnosis. In the proposed framework, we use U-Net down-sampling processes for extracting low-level deep learning features, which are shared by two sub-networks. The JCN forces the down-sampling processes to learn better lowlevel deep features, which lead to a better construct of segmentation masks. Meanwhile, two additional channels constructed by OTSU and super-pixel (SLIC) methods, are utilized as the guideline of the feature extraction. The proposed framework takes advantages of deep learning methods and classical methods, which can significantly improve the performances of all tasks. We evaluate the proposed framework on public dataset LIDCIDRI. Our framework achieves a promising Dice score of 86.43% in segmentation, 87.07% in malignancy level prediction, and convincing results in interpretable medical feature predictions.

Fused 3-Stage Image Segmentation for Pleural Effusion Cell Clusters

Sike Ma, Meng Zhao, Hao Wang, Fan Shi, Xuguo Sun, Shengyong Chen, Hong-Ning Dai

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Auto-TLDR; Coarse Segmentation of Stained and Stained Unstained Cell Clusters in pleural effusion using 3-stage segmentation method

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The appearance of tumor cell clusters in pleural effusion is usually a vital sign of cancer metastasis. Segmentation, as an indispensable basis, is of crucial importance for diagnosing, chemical treatment, and prognosis in patients. However, accurate segmentation of unstained cell clusters containing more detailed features than the fluorescent staining images remains to be a challenging problem due to the complex background and the unclear boundary. Therefore, in this paper, we propose a fused 3-stage image segmentation algorithm, namely Coarse segmentation-Mapping-Fine segmentation (CMF) to achieve unstained cell clusters from whole slide images. Firstly, we establish a tumor cell cluster dataset consisting of 107 sets of images, with each set containing one unstained image, one stained image, and one ground-truth image. Then, according to the features of the unstained and stained cell clusters, we propose a three-stage segmentation method: 1) Coarse segmentation on stained images to extract suspicious cell regions-Region of Interest (ROI); 2) Mapping this ROI to the corresponding unstained image to get the ROI of the unstained image (UI-ROI); 3) Fine Segmentation using improved automatic fuzzy clustering framework (AFCF) on the UI-ROI to get precise cell cluster boundaries. Experimental results on 107 sets of images demonstrate that the proposed algorithm can achieve better performance on unstained cell clusters with an F1 score of 90.40%.

MTGAN: Mask and Texture-Driven Generative Adversarial Network for Lung Nodule Segmentation

Wei Chen, Qiuli Wang, Kun Wang, Dan Yang, Xiaohong Zhang, Chen Liu, Yucong Li

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Auto-TLDR; Mask and Texture-driven Generative Adversarial Network for Lung Nodule Segmentation

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Accurate segmentation for lung nodules in lung computed tomography (CT) scans plays a key role in the early diagnosis of lung cancer. Many existing methods, especially UNet, have made significant progress in lung nodule segmentation. However, due to the complex shapes of lung nodules and the similarity of visual characteristics between nodules and lung tissues, an accurate segmentation with few false positives of lung nodules is still a challenging problem. Considering the fact that both boundary and texture information of lung nodules are important for obtaining an accurate segmentation result, we propose a novel Mask and Texture-driven Generative Adversarial Network (MTGAN) with a joint multi-scale L1 loss for lung nodule segmentation, which takes full advantages of U-Net and adversarial training. The proposed MTGAN leverages adversarial learning strategy guided by the boundary and texture information of lung nodules to generate more accurate segmentation results with lesser false positives. We validate our model with the LIDC–IDRI dataset, and experimental results show that our method achieves excellent segmentation results for a variety of lung nodules, especially for juxtapleural nodules and low-dense nodules. Without any bells and whistles, the proposed MTGAN achieves significant segmentation performance with the Dice similarity coefficient (DSC) of 85.24% on the LIDC–IDRI dataset.

EM-Net: Deep Learning for Electron Microscopy Image Segmentation

Afshin Khadangi, Thomas Boudier, Vijay Rajagopal

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Auto-TLDR; EM-net: Deep Convolutional Neural Network for Electron Microscopy Image Segmentation

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Recent high-throughput electron microscopy techniques such as focused ion-beam scanning electron microscopy (FIB-SEM) provide thousands of serial sections which assist the biologists in studying sub-cellular structures at high resolution and large volume. Low contrast of such images hinder image segmentation and 3D visualisation of these datasets. With recent advances in computer vision and deep learning, such datasets can be segmented and reconstructed in 3D with greater ease and speed than with previous approaches. However, these methods still rely on thousands of ground-truth samples for training and electron microscopy datasets require significant amounts of time for carefully curated manual annotations. We address these bottlenecks with EM-net, a scalable deep convolutional neural network for EM image segmentation. We have evaluated EM-net using two datasets, one of which belongs to an ongoing competition on EM stack segmentation since 2012. We show that EM-net variants achieve better performances than current deep learning methods using small- and medium-sized ground-truth datasets. We also show that the ensemble of top EM-net base classifiers outperforms other methods across a wide variety of evaluation metrics.

Triplet-Path Dilated Network for Detection and Segmentation of General Pathological Images

Jiaqi Luo, Zhicheng Zhao, Fei Su, Limei Guo

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Auto-TLDR; Triplet-path Network for One-Stage Object Detection and Segmentation in Pathological Images

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Deep learning has been widely applied in the field of medical image processing. However, compared with flourishing visual tasks in natural images, the progress achieved in pathological images is not remarkable, and detection and segmentation, which are among basic tasks of computer vision, are regarded as two independent tasks. In this paper, we make full use of existing datasets and construct a triplet-path network using dilated convolutions to cooperatively accomplish one-stage object detection and nuclei segmentation for general pathological images. First, in order to meet the requirement of detection and segmentation, a novel structure called triplet feature generation (TFG) is designed to extract high-resolution and multiscale features, where features from different layers can be properly integrated. Second, considering that pathological datasets are usually small, a location-aware and partially truncated loss function is proposed to improve the classification accuracy of datasets with few images and widely varying targets. We compare the performance of both object detection and instance segmentation with state-of-the-art methods. Experimental results demonstrate the effectiveness and efficiency of the proposed network on two datasets collected from multiple organs.

RescueNet: Joint Building Segmentation and Damage Assessment from Satellite Imagery

Rohit Gupta, Mubarak Shah

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Auto-TLDR; RescueNet: End-to-End Building Segmentation and Damage Classification for Humanitarian Aid and Disaster Response

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Accurate and fine-grained information about the extent of damage to buildings is essential for directing Humanitarian Aid and Disaster Response (HADR) operations in the immediate aftermath of any natural calamity. In recent years, satellite and UAV (drone) imagery has been used for this purpose, sometimes aided by computer vision algorithms. Existing Computer Vision approaches for building damage assessment typically rely on a two stage approach, consisting of building detection using an object detection model, followed by damage assessment through classification of the detected building tiles. These multi-stage methods are not end-to-end trainable, and suffer from poor overall results. We propose RescueNet, a unified model that can simultaneously segment buildings and assess the damage levels to individual buildings and can be trained end-to end. In order to to model the composite nature of this problem, we propose a novel localization aware loss function, which consists of a Binary Cross Entropy loss for building segmentation, and a foreground only selective Categorical Cross-Entropy loss for damage classification, and show significant improvement over the widely used Cross-Entropy loss. RescueNet is tested on the large scale and diverse xBD dataset and achieves significantly better building segmentation and damage classification performance than previous methods and achieves generalization across varied geographical regions and disaster types.

Coarse to Fine: Progressive and Multi-Task Learning for Salient Object Detection

Dong-Goo Kang, Sangwoo Park, Joonki Paik

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Auto-TLDR; Progressive and mutl-task learning scheme for salient object detection

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Most deep learning-based salient object detection (SOD) methods tried to manipulate the convolution block to effectively capture the context of object. In this paper, we propose a novel method, called progressive and mutl-task learning scheme, to extract the context of object by only manipulating the learning scheme without changing the network architecture. The progressive learning scheme is a method to grow the decoder progressively in the train phase. In other words, starting from easier low-resolution layers, it gradually adds high-resolution layers. Although the progressive learning successfullyl captures the context of object, its output boundary tends to be rough. To solve this problem, we also propose a multi-task learning (MTL) scheme that processes the object saliency map and contour in a single network jointly. The proposed MTL scheme trains the network in an edge-preserved direction through an auxiliary branch that learns contours. The proposed a learning scheme can be combined with other convolution block manipulation methods. Extensive experiments on five datasets show that the proposed method performs best compared with state-of-the-art methods in most cases.

Offset Curves Loss for Imbalanced Problem in Medical Segmentation

Ngan Le, Duc Toan Bui, Khoa Luu, Marios Savvides

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Auto-TLDR; Offset Curves Loss for Medical Image Segmentation

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Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to pixel-wise setting and imbalanced classes data problem. In this paper, we tackle those limitations by developing a new deep learning-based model which takes into account both higher feature level i.e. region inside contour, intermediate feature level i.e. offset curves around the contour and lower feature level i.e. contour. Our proposed Offset Curves (OsC) loss consists of three main fitting terms. The first fitting term focuses on pixel-wise level segmentation whereas the second fitting term acts as attention model which pays attention to the area around the boundaries (offset curves). The third terms plays a role as regularization term which takes the length of boundaries into account. We evaluate our proposed OsC loss on both 2D network and 3D network. Two common medical datasets, i.e. retina DRIVE and brain tumor BRATS 2018 datasets are used to benchmark our proposed loss performance. The experiments have showed that our proposed OsC loss function outperforms other mainstream loss functions such as Cross-Entropy, Dice, Focal on the most common segmentation networks Unet, FCN.

Point In: Counting Trees with Weakly Supervised Segmentation Network

Pinmo Tong, Shuhui Bu, Pengcheng Han

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Auto-TLDR; Weakly Tree counting using Deep Segmentation Network with Localization and Mask Prediction

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For tree counting tasks, since traditional image processing methods require expensive feature engineering and are not end-to-end frameworks, this will cause additional noise and cannot be optimized overall, so this method has not been widely used in recent trends of tree counting application. Recently, many deep learning based approaches are designed for this task because of the powerful feature extracting ability. The representative way is bounding box based supervised method, but time-consuming annotations are indispensable for them. Moreover, these methods are difficult to overcome the occlusion or overlap. To solve this problem, we propose a weakly tree counting network (WTCNet) based on deep segmentation network with only point supervision. It can simultaneously complete tree counting with localization and output mask of each tree at the same time. We first adopt a novel feature extractor network (FENet) to get features of input images, and then an effective strategy is introduced to deal with different mask predictions. In the end, we propose a basic localization guidance accompany with rectification guidance to train the network. We create two different datasets and select an existing challenging plant dataset to evaluate our method on three different tasks. Experimental results show the good performance improvement of our method compared with other existing methods. Further study shows that our method has great potential to reduce human labor and provide effective ground-truth masks and the results show the superiority of our method over the advanced methods.

A Benchmark Dataset for Segmenting Liver, Vasculature and Lesions from Large-Scale Computed Tomography Data

Bo Wang, Zhengqing Xu, Wei Xu, Qingsen Yan, Liang Zhang, Zheng You

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Auto-TLDR; The Biggest Treatment-Oriented Liver Cancer Dataset for Segmentation

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How to build a high-performance liver-related computer assisted diagnosis system is an open question of great interest. However, the performance of the state-of-art algorithm is always limited by the amount of data and quality of the label. To address this problem, we propose the biggest treatment-oriented liver cancer dataset for liver surgery and treatment planning. This dataset provides 216 cases (totally about 268K frames) scanned images in contrast-enhanced computed tomography (CT). We labeled all the CT images with the liver, liver vasculature and liver tumor segmentation ground truth for train and tune segmentation algorithms in advance. Based on that, we evaluate several recent and state-of-the-art segmentation algorithms, including 7 deep learning methods, on CT sequences. All results are compared to reference segmentations five error metrics that highlight different aspects of segmentation accuracy. In general, compared with previous datasets, our dataset is really a challenging dataset. To our knowledge, the proposed dataset and benchmark allow for the first time systematic exploration of such issues, and will be made available to allow for further research in this field.

Accurate Cell Segmentation in Digital Pathology Images Via Attention Enforced Networks

Zeyi Yao, Kaiqi Li, Guanhong Zhang, Yiwen Luo, Xiaoguang Zhou, Muyi Sun

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Auto-TLDR; AENet: Attention Enforced Network for Automatic Cell Segmentation

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Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more precise diagnosis, but also save much time and labor. However, this task suffers from stain variation, cell inhomogeneous intensities, background clutters and cells from different tissues. To address these issues, we propose an Attention Enforced Network (AENet), which is built on spatial attention module and channel attention module, to integrate local features with global dependencies and weight effective channels adaptively. Besides, we introduce a feature fusion branch to bridge high-level and low-level features. Finally, the marker controlled watershed algorithm is applied to post-process the predicted segmentation maps for reducing the fragmented regions. In the test stage, we present an individual color normalization method to deal with the stain variation problem. We evaluate this model on the MoNuSeg dataset. The quantitative comparisons against several prior methods demonstrate the priority of our approach.

Segmentation of Intracranial Aneurysm Remnant in MRA Using Dual-Attention Atrous Net

Subhashis Banerjee, Ashis Kumar Dhara, Johan Wikström, Robin Strand

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Auto-TLDR; Dual-Attention Atrous Net for Segmentation of Intracranial Aneurysm Remnant from MRA Images

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Due to the advancement of non-invasive medical imaging modalities like Magnetic Resonance Angiography (MRA), an increasing number of Intracranial Aneurysm (IA) cases are being reported in recent years. The IAs are typically treated by so-called endovascular coiling, where blood flow in the IA is prevented by embolization with a platinum coil. Accurate quantification of the IA Remnant (IAR), i.e. the volume with blood flow present post treatment is the utmost important factor in choosing the right treatment planning. This is typically done by manually segmenting the aneurysm remnant from the MRA volume. Since manual segmentation of volumetric images is a labour-intensive and error-prone process, development of an automatic volumetric segmentation method is required. Segmentation of small structures such as IA, that may largely vary in size, shape, and location is considered extremely difficult. Similar intensity distribution of IAs and surrounding blood vessels makes it more challenging and susceptible to false positive. In this paper we propose a novel 3D CNN architecture called Dual-Attention Atrous Net (DAtt-ANet), which can efficiently segment IAR volumes from MRA images by reconciling features at different scales using the proposed Parallel Atrous Unit (PAU) along with the use of self-attention mechanism for extracting fine-grained features and intra-class correlation. The proposed DAtt-ANet model is trained and evaluated on a clinical MRA image dataset (prospective research project, approved by the local ethical committee) of IAR consisting of 46 subjects, annotated by an expert radiologist from our group. We compared the proposed DAtt-ANet with five state-of-the-art CNN models based on their segmentation performance. The proposed DAtt-ANet outperformed all other methods and was able to achieve a five-fold cross-validation DICE score of $0.73\pm0.06$.

Machine-Learned Regularization and Polygonization of Building Segmentation Masks

Stefano Zorzi, Ksenia Bittner, Friedrich Fraundorfer

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Auto-TLDR; Automatic Regularization and Polygonization of Building Segmentation masks using Generative Adversarial Network

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We propose a machine learning based approach for automatic regularization and polygonization of building segmentation masks. Taking an image as input, we first predict building segmentation maps exploiting generic fully convolutional network (FCN). A generative adversarial network (GAN) is then involved to perform a regularization of building boundaries to make them more realistic, i.e., having more rectilinear outlines which construct right angles if required. This is achieved through the interplay between the discriminator which gives a probability of input image being true and generator that learns from discriminator’s response to create more realistic images. Finally, we train the backbone convolutional neural network (CNN) which is adapted to predict sparse outcomes corresponding to building corners out of regularized building segmentation results. Experiments on three building segmentation datasets demonstrate that the proposed method is not only capable of obtaining accurate results, but also of producing visually pleasing building outlines parameterized as polygons.

FOANet: A Focus of Attention Network with Application to Myocardium Segmentation

Zhou Zhao, Elodie Puybareau, Nicolas Boutry, Thierry Geraud

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Auto-TLDR; FOANet: A Hybrid Loss Function for Myocardium Segmentation of Cardiac Magnetic Resonance Images

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In myocardium segmentation of cardiac magnetic resonance images, ambiguities often appear near the boundaries of the target domains due to tissue similarities. To address this issue, we propose a new architecture, called FOANet, which can be decomposed in three main steps: a localization step, a Gaussian-based contrast enhancement step, and a segmentation step. This architecture is supplied with a hybrid loss function that guides the FOANet to study the transformation relationship between the input image and the corresponding label in a threelevel hierarchy (pixel-, patch- and map-level), which is helpful to improve segmentation and recovery of the boundaries. We demonstrate the efficiency of our approach on two public datasets in terms of regional and boundary segmentations.

Revisiting Sequence-To-Sequence Video Object Segmentation with Multi-Task Loss and Skip-Memory

Fatemeh Azimi, Benjamin Bischke, Sebastian Palacio, Federico Raue, Jörn Hees, Andreas Dengel

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Auto-TLDR; Sequence-to-Sequence Learning for Video Object Segmentation

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Video Object Segmentation (VOS) is an active research area of the visual domain. One of its fundamental sub-tasks is semi-supervised / one-shot learning: given only the segmentation mask for the first frame, the task is to provide pixel-accurate masks for the object over the rest of the sequence. Despite much progress in the last years, we noticed that many of the existing approaches lose objects in longer sequences, especially when the object is small or briefly occluded. In this work, we build upon a sequence-to-sequence approach that employs an encoder-decoder architecture together with a memory module for exploiting the sequential data. We further improve this approach by proposing a model that manipulates multi-scale spatio-temporal information using memory-equipped skip connections. Furthermore, we incorporate an auxiliary task based on distance classification which greatly enhances the quality of edges in segmentation masks. We compare our approach to the state of the art and show considerable improvement in the contour accuracy metric and the overall segmentation accuracy.

CAggNet: Crossing Aggregation Network for Medical Image Segmentation

Xu Cao, Yanghao Lin

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Auto-TLDR; Crossing Aggregation Network for Medical Image Segmentation

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In this paper, we present Crossing Aggregation Network (CAggNet), a novel densely connected semantic segmentation method for medical image analysis. The crossing aggregation network absorbs the idea of deep layer aggregation and makes significant innovations in layer connection and semantic information fusion. In this architecture, the traditional skip-connection structure of general U-Net is replaced by aggregations of multi-level down-sampling and up-sampling layers. This enables the network to fuse information interactively flows at different levels of layers in semantic segmentation. It also introduces weighted aggregation module to aggregate multi-scale output information. We have evaluated and compared our CAggNet with several advanced U-Net based methods in two public medical image datasets, including the 2018 Data Science Bowl nuclei detection dataset and the 2015 MICCAI gland segmentation competition dataset. Experimental results indicate that CAggNet improves medical object recognition and achieves a more accurate and efficient segmentation compared to existing improved U-Net and UNet++ structure.

Do Not Treat Boundaries and Regions Differently: An Example on Heart Left Atrial Segmentation

Zhou Zhao, Elodie Puybareau, Nicolas Boutry, Thierry Geraud

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Auto-TLDR; Attention Full Convolutional Network for Atrial Segmentation using ResNet-101 Architecture

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Atrial fibrillation is the most common heart rhythm disease. Due to a lack of understanding in matter of underlying atrial structures, current treatments are still not satisfying. Recently, with the popularity of deep learning, many segmentation methods based on fully convolutional networks have been proposed to analyze atrial structures, especially from late gadolinium-enhanced magnetic resonance imaging. However, two problems still occur: 1) segmentation results include the atrial-like background; 2) boundaries are very hard to segment. Most segmentation approaches design a specific network that mainly focuses on the regions, to the detriment of the boundaries. Therefore, this paper proposes an attention full convolutional network framework based on the ResNet-101 architecture, which focuses on boundaries as much as on regions. The additional attention module is added to have the network pay more attention on regions and then to reduce the impact of the misleading similarity of neighboring tissues. We also use a hybrid loss composed of a region loss and a boundary loss to treat boundaries and regions at the same time. We demonstrate the efficiency of the proposed approach on the MICCAI 2018 Atrial Segmentation Challenge public dataset.

A Deep Learning Approach for the Segmentation of Myocardial Diseases

Khawala Brahim, Abdull Qayyum, Alain Lalande, Arnaud Boucher, Anis Sakly, Fabrice Meriaudeau

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Auto-TLDR; Segmentation of Myocardium Infarction Using Late GADEMRI and SegU-Net

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Cardiac left ventricular (LV) segmentation is of paramount essential step for both diagnosis and treatment of cardiac pathologies such as ischemia, myocardial infarction, arrhythmia and myocarditis. However, this segmentation is challenging due to high variability across patients and the potential lack of contrast between structures. In this work, we propose and evaluate a (2.5D) SegU-Net model based on the fusion of two deep learning techniques (U-Net and Seg-Net) for automated LGEMRI (Late gadolinium enhanced magnetic resonance imaging) myocardial disease (infarct core and no reflow region) quantification in a new multifield expert annotated dataset. Given that the scar tissue represents a small part of the whole MRI slices, we focused on myocardium area. Segmentation results show that this preprocessing step facilitate the learning procedure. In order to solve the class imbalance problem, we propose to apply the Jaccard loss and the Focal Loss as optimization loss function and to integrate a class weights strategy into the objective function. Late combination has been used to merge the output of the best trained models on a different set of hyperparameters. The final network segmentation performances will be useful for future comparison of new method to the current related work for this task. A total number of 2237 of slices (320 cases) were used for training/validation and 210 slices (35 cases) were used for testing. Experiments over our proposed dataset, using several evaluation metrics such Jaccard distance (IOU), Accuracy and Dice similarity coefficient (DSC), demonstrate efficiency performance in quantifying different zones of myocardium infarction across various patients. As compared to the second intra-observer study, our testing results showed that the SegUNet prediction model leads to these average dice coefficients over all segmented tissue classes, respectively : 'Background': 0.99999, 'Myocardium': 0.99434, 'Infarctus': 0.95587, 'Noreflow': 0.78187.

DE-Net: Dilated Encoder Network for Automated Tongue Segmentation

Hui Tang, Bin Wang, Jun Zhou, Yongsheng Gao

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Auto-TLDR; Automated Tongue Image Segmentation using De-Net

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Automated tongue recognition is a growing research field due to global demand for personal health care. Using mobile devices to take tongue pictures is convenient and of low cost for tongue recognition. It is particularly suitable for self-health evaluation of the public. However, images taken by mobile devices are easily affected by various imaging environment, which makes fine segmentation a more challenging task compared with those taken by specialized acquisition devices. Deep learning approaches are promising for tongue image segmentation because they have powerful feature learning and representation capability. However, the successive pooling operations in these methods lead to loss of information on image details, making them fail when segmenting low-quality images captured by mobile devices. To address this issue, we propose a dilated encoder network (DE-Net) to capture more high-level features and get high-resolution output for automated tongue image segmentation. In addition, we construct two tongue image datasets which contain images taken by specialized devices and mobile devices, respectively, to verify the effectiveness of the proposed method. Experimental results on both datasets demonstrate that the proposed method outperforms the state-of-the-art methods in tongue image segmentation.

A Lumen Segmentation Method in Ureteroscopy Images Based on a Deep Residual U-Net Architecture

Jorge Lazo, Marzullo Aldo, Sara Moccia, Michele Catellani, Benoit Rosa, Elena De Momi, Michel De Mathelin, Francesco Calimeri

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Auto-TLDR; A Deep Neural Network for Ureteroscopy with Residual Units

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Ureteroscopy is becoming the first surgical treatment option for the majority of urinary affections. This procedure is carried out using an endoscope which provides the surgeon with the visual and spatial information necessary to navigate inside the urinary tract. Having in mind the development of surgical assistance systems, that could enhance the performance of surgeon, the task of lumen segmentation is a fundamental part since this is the visual reference which marks the path that the endoscope should follow. This is something that has not been analyzed in ureteroscopy data before. However, this task presents several challenges given the image quality and the conditions itself of ureteroscopy procedures. In this paper, we study the implementation of a Deep Neural Network which exploits the advantage of residual units in an architecture based on U-Net. For the training of these networks, we analyze the use of two different color spaces: gray-scale and RGB data images. We found that training on gray-scale images gives the best results obtaining mean values of Dice Score, Precision, and Recall of 0.73, 0.58, and 0.92 respectively. The results obtained show that the use of residual U-Net could be a suitable model for further development for a computer-aided system for navigation and guidance through the urinary system.

Uncertainty Guided Recognition of Tiny Craters on the Moon

Thorsten Wilhelm, Christian Wöhler

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Auto-TLDR; Accurately Detecting Tiny Craters in Remote Sensed Images Using Deep Neural Networks

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Accurately detecting craters in remotely sensed images is an important task when analysing the properties of planetary bodies. Commonly, only large craters in the range of several kilometres are detected. In this work we provide the first example of automatically detecting tiny craters in the range of several meters with the help of a deep neural network by using only a small set of annotated craters. Additionally, we propose a novel way to group overlapping detections and replace the commonly used non-maximum suppression with a probabilistic treatment. As a result, we receive valuable uncertainty estimates of the detections and the aggregated detections are shown to be vastly superior.

Human Embryo Cell Centroid Localization and Counting in Time-Lapse Sequences

Lisette Lockhart, Parvaneh Saeedi, Jason Au, Jon Havelock

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Auto-TLDR; Automated Time-Lapse Estimation of Embryo Cell Stage in Time-lapse Sequences

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Couples suffering from infertility issues often use In Vitro Fertilization (IVF) treatment to give birth. Continuous embryo monitoring with time-lapse imaging enables time-based development metrics alongside visual features to assess an embryo’s quality before transfer. Tracking embryonic cell development provides valuable information about its likelihood of leading to a positive pregnancy. Automating this task is challenging due to cell overlap, occlusion, and variation. In this paper, cell stage is identified by counting detected cell centroids in early embryo time-lapse sequences. A convolutional regression network is trained on Gaussian-annotated centroid maps to localize cell centroids. Added network attention blocks encode spatio-temporal relationship in time-lapse sequences to emphasize relevant features in the current frame based on previous frame and cell (i.e. blastomere) movement. The proposed approach was applied to 108 embryo sequences including 1- to 4-cell stage, achieving cell centroid localization distance error of 3.98 pixels, cell detection rate 80.9%, and cell counting accuracy of 80.2%.

Transfer Learning through Weighted Loss Function and Group Normalization for Vessel Segmentation from Retinal Images

Abdullah Sarhan, Jon Rokne, Reda Alhajj, Andrew Crichton

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Auto-TLDR; Deep Learning for Segmentation of Blood Vessels in Retinal Images

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The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic cup and hence determine if there are damages to these areas. Moreover, the structure of the vessels can help in diagnosing glaucoma. The rapid development of digital imaging and computer-vision techniques has increased the potential for developing approaches for segmenting retinal vessels. In this paper, we propose an approach for segmenting retinal vessels that uses deep learning along with transfer learning. We adapted the U-Net structure to use a customized InceptionV3 as the encoder and used multiple skip connections to form the decoder. Moreover, we used a weighted loss function to handle the issue of class imbalance in retinal images. Furthermore, we contributed a new dataset to this field. We tested our approach on six publicly available datasets and a newly created dataset. We achieved an average accuracy of 95.60\% and a Dice coefficient of 80.98\%. The results obtained from comprehensive experiments demonstrate the robustness of our approach to the segmentation of blood vessels in retinal images obtained from different sources. Our approach results in greater segmentation accuracy than other approaches.

BiLuNet: A Multi-Path Network for Semantic Segmentation on X-Ray Images

Van Luan Tran, Huei-Yung Lin, Rachel Liu, Chun-Han Tseng, Chun-Han Tseng

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Auto-TLDR; BiLuNet: Multi-path Convolutional Neural Network for Semantic Segmentation of Lumbar vertebrae, sacrum,

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Semantic segmentation and shape detection of lumbar vertebrae, sacrum, and femoral heads from clinical X-ray images are important and challenging tasks. In this paper, we propose a new multi-path convolutional neural network, BiLuNet, for semantic segmentation on X-ray images. The network is capable of medical image segmentation with very limited training data. With the shape fitting of the bones, we can identify the location of the target regions very accurately for lumbar vertebra inspection. We collected our dataset and annotated by doctors for model training and performance evaluation. Compared to the state-of-the-art methods, the proposed technique provides better mIoUs and higher success rates with the same training data. The experimental results have demonstrated the feasibility of our network to perform semantic segmentation for lumbar vertebrae, sacrum, and femoral heads.

A Hierarchical Framework for Leaf Instance Segmentation: Application to Plant Phenotyping

Swati Bhugra, Kanish Garg, Santanu Chaudhury, Brejesh Lall

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Auto-TLDR; Under-segmentation of plant image using a graph based formulation to extract leaf shape knowledge for the task of leaf instance segmentation

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Image based analysis of plants is a high-throughput and non-invasive approach to study plant traits. Based on plant image data, the quantitative estimation of many plant traits (leaf area index, biomass etc.) is associated with accurate segmentation of individual leaves. However, this task is challenging due to the presence of overlapped leaves and lack of discernible boundaries between them. In addition, variability in leaf shapes and arrangement among different plant species limits the broad utilisation of current leaf instance segmentation algorithms. In this paper, we propose a novel framework that relies on under-segmentation of plant image using a graph based formulation to extract leaf shape knowledge for the task of leaf instance segmentation. These shape priors are generated based on leaf shape characteristics independent of plant species. We demonstrate the performance of the proposed framework across multiple plant dataset i.e. Arabidopsis, Komatsuna and Salad. Experimental results indicate its broad utility.

NephCNN: A Deep-Learning Framework for Vessel Segmentation in Nephrectomy Laparoscopic Videos

Alessandro Casella, Sara Moccia, Chiara Carlini, Emanuele Frontoni, Elena De Momi, Leonardo Mattos

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Auto-TLDR; Adversarial Fully Convolutional Neural Networks for kidney vessel segmentation from nephrectomy laparoscopic videos

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Objective: In the last years, Robot-assisted partial nephrectomy (RAPN) is establishing as elected treatment for renal cell carcinoma (RCC). Reduced field of view, field occlusions by surgical tools, and reduced maneuverability may potentially cause accidents, such as unwanted vessel resection with consequent bleeding. Surgical Data Science (SDS) can provide effective context-aware tools for supporting surgeons. However, currently no tools have been exploited for automatic vessels segmentation from nephrectomy laparoscopic videos. Herein, we propose a new approach based on adversarial Fully Convolutional Neural Networks (FCNNs) to kidney vessel segmentation from nephrectomy laparoscopic vision. Methods: The proposed approach enhances existing segmentation framework by (i) encoding 3D kernels for spatio-temporal features extraction to enforce pixel connectivity in time, and (ii) perform training in adversarial fashion, which constrains vessels shape. Results: We performed a preliminary study using 8 different RAPN videos (1871 frames), the first in the field, achieving a median Dice Similarity Coefficient of 71.76%. Conclusions: Results showed that the proposed approach could be a valuable solution with a view to assist surgeon during RAPN.

Segmentation of Axillary and Supraclavicular Tumoral Lymph Nodes in PET/CT: A Hybrid CNN/Component-Tree Approach

Diana Lucia Farfan Cabrera, Nicolas Gogin, David Morland, Benoît Naegel, Dimitri Papathanassiou, Nicolas Passat

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Auto-TLDR; Coupling Convolutional Neural Networks and Component-Trees for Lymph node Segmentation from PET/CT Images

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The analysis of axillary and supraclavicular lymph nodes is a primary prognostic factor for the staging of breast cancer. However, due to the size of lymph nodes and the low resolution of PET data, their segmentation is challenging. We investigate the relevance of considering axillary and supraclavicular lymph node segmentation from PET/CT images by coupling Convolutional Neural Networks (CNNs) and Component-Trees (C-Trees). Building upon the U-Net architecture, we propose a framework that couples a multi-modal U-Net fed with PET and CT, coupled with a hierarchical model obtained from the PET that provides additional high-level region-based features as input channels. Our working hypotheses are twofold. First, we take advantage of both anatomical information from CT for detecting the nodes, and from functional information from PET for detecting the pathological ones. Second, we consider region-based attributes extracted from C-Tree analysis of 3D PET/CT images to improve the CNN segmentation. We carried out experiments on a dataset of 240 pathological lymph nodes from 52 patients scans, and compared our outputs with human expert-defined ground-truth, leading to promising results.

Approach for Document Detection by Contours and Contrasts

Daniil Tropin, Sergey Ilyuhin, Dmitry Nikolaev, Vladimir V. Arlazarov

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Auto-TLDR; A countor-based method for arbitrary document detection on a mobile device

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This paper considers the task of arbitrary document detection performed on a mobile device. The classical contour-based approach often mishandles cases with occlusion, complex background, or blur. Region-based approach, which relies on the contrast between object and background, does not have limitations, however its known implementations are highly resource-consuming. We propose a modification of a countor-based method, in which the competing hypotheses of the contour location are ranked according to the contrast between the areas inside and outside the border. In the performed experiments such modification leads to the 40% decrease of alternatives ordering errors and 10% decrease of the overall number of detection errors. We updated state-of-the-art performance on the open MIDV-500 dataset and demonstrated competitive results with the state-of-the-art on the SmartDoc dataset.

CT-UNet: An Improved Neural Network Based on U-Net for Building Segmentation in Remote Sensing Images

Huanran Ye, Sheng Liu, Kun Jin, Haohao Cheng

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Auto-TLDR; Context-Transfer-UNet: A UNet-based Network for Building Segmentation in Remote Sensing Images

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With the proliferation of remote sensing images, how to segment buildings more accurately in remote sensing images is a critical challenge. First, the high resolution leads to blurred boundaries in the extracted building maps. Second, the similarity between buildings and background results in intra-class inconsistency. To address these two problems, we propose an UNet-based network named Context-Transfer-UNet (CT-UNet). Specifically, we design Dense Boundary Block (DBB). Dense Block utilizes reuse mechanism to refine features and increase recognition capabilities. Boundary Block introduces the low-level spatial information to solve the fuzzy boundary problem. Then, to handle intra-class inconsistency, we construct Spatial Channel Attention Block (SCAB). It combines context space information and selects more distinguishable features from space and channel. Finally, we propose a novel loss function to enhance the purpose of loss by adding evaluation indicator. Based on our proposed CT-UNet, we achieve 85.33% mean IoU on the Inria dataset and 91.00% mean IoU on the WHU dataset, which outperforms our baseline (U-Net ResNet-34) by 3.76% and Web-Net by 2.24%.

Early Wildfire Smoke Detection in Videos

Taanya Gupta, Hengyue Liu, Bir Bhanu

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Auto-TLDR; Semi-supervised Spatio-Temporal Video Object Segmentation for Automatic Detection of Smoke in Videos during Forest Fire

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Recent advances in unmanned aerial vehicles and camera technology have proven useful for the detection of smoke that emerges above the trees during a forest fire. Automatic detection of smoke in videos is of great interest to Fire department. To date, in most parts of the world, the fire is not detected in its early stage and generally it turns catastrophic. This paper introduces a novel technique that integrates spatial and temporal features in a deep learning framework using semi-supervised spatio-temporal video object segmentation and dense optical flow. However, detecting this smoke in the presence of haze and without the labeled data is difficult. Considering the visibility of haze in the sky, a dark channel pre-processing method is used that reduces the amount of haze in video frames and consequently improves the detection results. Online training is performed on a video at the time of testing that reduces the need for ground-truth data. Tests using the publicly available video datasets show that the proposed algorithms outperform previous work and they are robust across different wildfire-threatened locations.

3D Medical Multi-Modal Segmentation Network Guided by Multi-Source Correlation Constraint

Tongxue Zhou, Stéphane Canu, Pierre Vera, Su Ruan

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Auto-TLDR; Multi-modality Segmentation with Correlation Constrained Network

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In the field of multimodal segmentation, the correlation between different modalities can be considered for improving the segmentation results. In this paper, we propose a multi-modality segmentation network with a correlation constraint. Our network includes N model-independent encoding paths with N image sources, a correlation constrain block, a feature fusion block, and a decoding path. The model-independent encoding path can capture modality-specific features from the N modalities. Since there exists a strong correlation between different modalities, we first propose a linear correlation block to learn the correlation between modalities, then a loss function is used to guide the network to learn the correlated features based on the correlation representation block. This block forces the network to learn the latent correlated features which are more relevant for segmentation. Considering that not all the features extracted from the encoders are useful for segmentation, we propose to use dual attention based fusion block to recalibrate the features along the modality and spatial paths, which can suppress less informative features and emphasize the useful ones. The fused feature representation is finally projected by the decoder to obtain the segmentation result. Our experiment results tested on BraTS-2018 dataset for brain tumor segmentation demonstrate the effectiveness of our proposed method.

A Multi-Task Contextual Atrous Residual Network for Brain Tumor Detection & Segmentation

Ngan Le, Kashu Yamazaki, Quach Kha Gia, Thanh-Dat Truong, Marios Savvides

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Auto-TLDR; Contextual Brain Tumor Segmentation Using 3D atrous Residual Networks and Cascaded Structures

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In recent years, deep neural networks have achieved state-of-the-art performance in a variety of recognition and segmentation tasks in medical imaging including brain tumor segmentation. We investigate that segmenting brain tumor is facing to the imbalanced data problem where the number of pixels belonging to background class (non tumor pixel) is much larger than the number of pixels belonging to foreground class (tumor pixel). To address this problem, we propose a multi-task network which is formed as a cascaded structure and designed to share the feature maps. Our model consists of two targets, i.e., (i) effectively differentiating brain tumor regions and (ii) estimating brain tumor masks. The first task is performed by our proposed contextual brain tumor detection network, which plays the role of an attention gate and focuses on the region around brain tumor only while ignore the background (non tumor area). Instead of processing every pixel, our contextual brain tumor detection network only processes contextual regions around ground-truth instances and this strategy helps to produce meaningful regions proposals. The second task is built upon a 3D atrous residual network and under an encode-decode network in order to effectively segment both large and small objects (brain tumor). Our 3D atrous residual network is designed with a skip connection to enables the gradient from the deep layers to be directly propagated to shallow layers, thus, features of different depths are preserved and used for refining each other. In order to incorporate larger contextual information in volume MRI data, our network is designed by 3D atrous convolution with various kernel sizes, which enlarges the receptive field of filters. Our proposed network has been evaluated on various datasets including BRATS2015, BRATS2017 and BRATS2018 datasets with both validation set and testing set. Our performance has been benchmarked by both region-based metrics and surface-based metrics. We also have conducted comparisons against state-of-the-art approaches.

Quantization in Relative Gradient Angle Domain for Building Polygon Estimation

Yuhao Chen, Yifan Wu, Linlin Xu, Alexander Wong

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Auto-TLDR; Relative Gradient Angle Transform for Building Footprint Extraction from Remote Sensing Data

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Building footprint extraction in remote sensing data benefits many important applications, such as urban planning and population estimation. Recently, rapid development of Convolutional Neural Networks (CNNs) and open-sourced high resolution satellite building image datasets have pushed the performance boundary further for automated building extractions. However, CNN approaches often generate imprecise building morphologies including noisy edges and round corners. In this paper, we leverage the performance of CNNs, and propose a module that uses prior knowledge of building corners to create angular and concise building polygons from CNN segmentation outputs. We describe a new transform, Relative Gradient Angle Transform (RGA Transform) that converts object contours from time vs. space to time vs. angle. We propose a new shape descriptor, Boundary Orientation Relation Set (BORS), to describe angle relationship between edges in RGA domain, such as orthogonality and parallelism. Finally, we develop an energy minimization framework that makes use of the angle relationship in BORS to straighten edges and reconstruct sharp corners, and the resulting corners create a polygon. Experimental results demonstrate that our method refines CNN output from a rounded approximation to a more clear-cut angular shape of the building footprint.

Breast Anatomy Enriched Tumor Saliency Estimation

Fei Xu, Yingtao Zhang, Heng-Da Cheng, Jianrui Ding, Boyu Zhang, Chunping Ning, Ying Wang

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Auto-TLDR; Tumor Saliency Estimation for Breast Ultrasound using enriched breast anatomy knowledge

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Breast cancer investigation is of great significance and developing tumor detection methodologies is a critical need. However, it is a challenging task for breast cancer detection using breast ultrasound (BUS) images due to the complicated breast structure and poor quality of the images. In this paper, we propose a novel tumor saliency estimation (TSE) model guided by enriched breast anatomy knowledge to localize the tumor. First, the breast anatomy layers are generated by a deep neural network. Then we refine the layers by integrating a non-semantic breast anatomy model to solve the problems of incomplete mammary layers. Meanwhile, a new background map generation method weighted by the semantic probability and spatial distance is proposed to improve the performance. The experiment demonstrates that the proposed method with the new background map outperforms four state-of-the-art TSE models with increasing 10% of F_meansure on the public BUS dataset.

Video Semantic Segmentation Using Deep Multi-View Representation Learning

Akrem Sellami, Salvatore Tabbone

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Auto-TLDR; Deep Multi-view Representation Learning for Video Object Segmentation

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In this paper, we propose a deep learning model based on deep multi-view representation learning, to address the video object segmentation task. The proposed model emphasizes the importance of the inherent correlation between video frames and incorporates a multi-view representation learning based on deep canonically correlated autoencoders. The multi-view representation learning in our model provides an efficient mechanism for capturing inherent correlations by jointly extracting useful features and learning better representation into a joint feature space, i.e., shared representation. To increase the training data and the learning capacity, we train the proposed model with pairs of video frames, i.e., $F_{a}$ and $F_{b}$. During the segmentation phase, the deep canonically correlated autoencoders model encodes useful features by processing multiple reference frames together, which is used to detect the frequently reappearing. Our model enhances the state-of-the-art deep learning-based methods that mainly focus on learning discriminative foreground representations over appearance and motion. Experimental results over two large benchmarks demonstrate the ability of the proposed method to outperform competitive approaches and to reach good performances, in terms of semantic segmentation.

Deep Recurrent-Convolutional Model for AutomatedSegmentation of Craniomaxillofacial CT Scans

Francesca Murabito, Simone Palazzo, Federica Salanitri Proietto, Francesco Rundo, Ulas Bagci, Daniela Giordano, Rosalia Leonardi, Concetto Spampinato

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Auto-TLDR; Automated Segmentation of Anatomical Structures in Craniomaxillofacial CT Scans using Fully Convolutional Deep Networks

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In this paper we define a deep learning architecture for automated segmentation of anatomical structures in Craniomaxillofacial (CMF) CT scans that leverages the recent success of encoder-decoder models for semantic segmentation of natural images. In particular, we propose a fully convolutional deep network that combines the advantages of recent fully convolutional models, such as Tiramisu, with squeeze-and-excitation blocks for feature recalibration, integrated with convolutional LSTMs to model spatio-temporal correlations between consecutive slices. The proposed segmentation network shows superior performance and generalization capabilities (to different structures and imaging modalities) than state of the art methods on automated segmentation of CMF structures (e.g., mandibles and airways) in several standard benchmarks (e.g., MICCAI datasets) and on new datasets proposed herein, effectively facing shape variability.

Learn to Segment Retinal Lesions and Beyond

Qijie Wei, Xirong Li, Weihong Yu, Xiao Zhang, Yongpeng Zhang, Bojie Hu, Bin Mo, Di Gong, Ning Chen, Dayong Ding, Youxin Chen

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Auto-TLDR; Multi-task Lesion Segmentation and Disease Classification for Diabetic Retinopathy Grading

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Towards automated retinal screening, this paper makes an endeavor to simultaneously achieve pixel-level retinal lesion segmentation and image-level disease classification. Such a multi-task approach is crucial for accurate and clinically interpretable disease diagnosis. Prior art is insufficient due to three challenges, i.e., lesions lacking objective boundaries, clinical importance of lesions irrelevant to their size, and the lack of one-to-one correspondence between lesion and disease classes. This paper attacks the three challenges in the context of diabetic retinopathy (DR) grading. We propose Lesion-Net, a new variant of fully convolutional networks, with its expansive path re- designed to tackle the first challenge. A dual Dice loss that leverages both semantic segmentation and image classification losses is introduced to resolve the second challenge. Lastly, we build a multi-task network that employs Lesion-Net as a side- attention branch for both DR grading and result interpretation. A set of 12K fundus images is manually segmented by 45 ophthalmologists for 8 DR-related lesions, resulting in 290K manual segments in total. Extensive experiments on this large- scale dataset show that our proposed approach surpasses the prior art for multiple tasks including lesion segmentation, lesion classification and DR grading.

3D Semantic Labeling of Photogrammetry Meshes Based on Active Learning

Mengqi Rong, Shuhan Shen, Zhanyi Hu

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Auto-TLDR; 3D Semantic Expression of Urban Scenes Based on Active Learning

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As different urban scenes are similar but still not completely consistent, coupled with the complexity of labeling directly in 3D, high-level understanding of 3D scenes has always been a tricky problem. In this paper, we propose a procedural approach for 3D semantic expression of urban scenes based on active learning. We first start with a small labeled image set to fine-tune a semantic segmentation network and then project its probability map onto a 3D mesh model for fusion, finally outputs a 3D semantic mesh model in which each facet has a semantic label and a heat model showing each facet’s confidence. Our key observation is that our algorithm is iterative, in each iteration, we use the output semantic model as a supervision to select several valuable images for annotation to co-participate in the fine-tuning for overall improvement. In this way, we reduce the workload of labeling but not the quality of 3D semantic model. Using urban areas from two different cities, we show the potential of our method and demonstrate its effectiveness.

Progressive Adversarial Semantic Segmentation

Abdullah-Al-Zubaer Imran, Demetri Terzopoulos

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Auto-TLDR; Progressive Adversarial Semantic Segmentation for End-to-End Medical Image Segmenting

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Medical image computing has advanced rapidly with the advent of deep learning techniques such as convolutional neural networks. Deep convolutional neural networks can perform exceedingly well given full supervision. However, the success of such fully-supervised models for various image analysis tasks (e.g., anatomy or lesion segmentation from medical images) is limited to the availability of massive amounts of labeled data. Given small sample sizes, such models are prohibitively data biased with large domain shift. To tackle this problem, we propose a novel end-to-end medical image segmentation model, namely Progressive Adversarial Semantic Segmentation (PASS), which can make improved segmentation predictions without requiring any domain-specific data during training time. Our extensive experimentation with 8 public diabetic retinopathy and chest X-ray datasets, confirms the effectiveness of PASS for accurate vascular and pulmonary segmentation, both for in-domain and cross-domain evaluations.

A Comparison of Neural Network Approaches for Melanoma Classification

Maria Frasca, Michele Nappi, Michele Risi, Genoveffa Tortora, Alessia Auriemma Citarella

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Auto-TLDR; Classification of Melanoma Using Deep Neural Network Methodologies

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Melanoma is the deadliest form of skin cancer and it is diagnosed mainly visually, starting from initial clinical screening and followed by dermoscopic analysis, biopsy and histopathological examination. A dermatologist’s recognition of melanoma may be subject to errors and may take some time to diagnose it. In this regard, deep learning can be useful in the study and classification of skin cancer. In particular, by classifying images with Deep Neural Network methodologies, it is possible to obtain comparable or even superior results compared to those of dermatologists. In this paper, we propose a methodology for the classification of melanoma by adopting different deep learning techniques applied to a common dataset, composed of images from the ISIC dataset and consisting of different types of skin diseases, including melanoma on which we applied a specific pre-processing phase. In particular, a comparison of the results is performed in order to select the best effective neural network to be applied to the problem of recognition and classification of melanoma. Moreover, we also evaluate the impact of the pre- processing phase on the final classification. Different metrics such as accuracy, sensitivity, and specificity have been selected to assess the goodness of the adopted neural networks and compare them also with the manual classification of dermatologists.

Learning Defects in Old Movies from Manually Assisted Restoration

Arthur Renaudeau, Travis Seng, Axel Carlier, Jean-Denis Durou, Fabien Pierre, Francois Lauze, Jean-François Aujol

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Auto-TLDR; U-Net: Detecting Defects in Old Movies by Inpainting Techniques

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We propose to detect defects in old movies, as the first step of a larger framework of old movies restoration by inpainting techniques. The specificity of our work is to learn a film restorer's expertise from a pair of sequences, composed of a movie with defects, and the same movie which was semi-automatically restored with the help of a specialized software. In order to detect those defects with minimal human interaction and further reduce the time spent for a restoration, we feed a U-Net with consecutive defective frames as input to detect the unexpected variations of pixel intensity over space and time. Since the output of the network is a mask of defect location, we first have to create the dataset of mask frames on the basis of restored frames from the software used by the film restorer, instead of classical synthetic ground truth, which is not available. These masks are estimated by computing the absolute difference between restored frames and defectuous frames, combined with thresholding and morphological closing. Our network succeeds in automatically detecting real defects with more precision than the manual selection with an all-encompassing shape, including some the expert restorer could have missed for lack of time.

DARN: Deep Attentive Refinement Network for Liver Tumor Segmentation from 3D CT Volume

Yao Zhang, Jiang Tian, Cheng Zhong, Yang Zhang, Zhongchao Shi, Zhiqiang He

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Auto-TLDR; Deep Attentive Refinement Network for Liver Tumor Segmentation from 3D Computed Tomography Using Multi-Level Features

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Automatic liver tumor segmentation from 3D Computed Tomography (CT) is a necessary prerequisite in the interventions of hepatic abnormalities and surgery planning. However, accurate liver tumor segmentation remains challenging due to the large variability of tumor sizes and inhomogeneous texture. Recent advances based on Fully Convolutional Network (FCN) in liver tumor segmentation draw on success of learning discriminative multi-level features. In this paper, we propose a Deep Attentive Refinement Network (DARN) for improved liver tumor segmentation from CT volumes by fully exploiting both low and high level features embedded in different layers of FCN. Different from existing works, we exploit attention mechanism to leverage the relation of different levels of features encoded in different layers of FCN. Specifically, we introduce a Semantic Attention Refinement (SemRef) module to selectively emphasize global semantic information in low level features with the guidance of high level ones, and a Spatial Attention Refinement (SpaRef) module to adaptively enhance spatial details in high level features with the guidance of low level ones. We evaluate our network on the public MICCAI 2017 Liver Tumor Segmentation Challenge dataset (LiTS dataset) and it achieves state-of-the-art performance. The proposed refinement modules are an effective strategy to exploit multi-level features and has great potential to generalize to other medical image segmentation tasks.

Aerial Road Segmentation in the Presence of Topological Label Noise

Corentin Henry, Friedrich Fraundorfer, Eleonora Vig

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Auto-TLDR; Improving Road Segmentation with Noise-Aware U-Nets for Fine-Grained Topology delineation

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The availability of large-scale annotated datasets has enabled Fully-Convolutional Neural Networks to reach outstanding performance on road extraction in aerial images. However, high-quality pixel-level annotation is expensive to produce and even manually labeled data often contains topological errors. Trading off quality for quantity, many datasets rely on already available yet noisy labels, for example from OpenStreetMap. In this paper, we explore the training of custom U-Nets built with ResNet and DenseNet backbones using noise-aware losses that are robust towards label omission and registration noise. We perform an extensive evaluation of standard and noise-aware losses, including a novel Bootstrapped DICE-Coefficient loss, on two challenging road segmentation benchmarks. Our losses yield a consistent improvement in overall extraction quality and exhibit a strong capacity to cope with severe label noise. Our method generalizes well to two other fine-grained topology delineation tasks: surface crack detection for quality inspection and cell membrane extraction in electron microscopy imagery.

Motion U-Net: Multi-Cue Encoder-Decoder Network for Motion Segmentation

Gani Rahmon, Filiz Bunyak, Kannappan Palaniappan

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Auto-TLDR; Motion U-Net: A Deep Learning Framework for Robust Moving Object Detection under Challenging Conditions

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Detection of moving objects is a critical first step in many computer vision applications. Several algorithms for motion and change detection were proposed. However, many of these approaches lack the ability to handle challenging real-world scenarios. Recently, deep learning approaches started to produce impressive solutions to computer vision tasks, particularly for detection and segmentation. Many existing deep learning networks proposed for moving object detection rely only on spatial appearance cues. In this paper, we propose a novel multi-cue and multi-stream network, Motion U-Net (MU-Net), which integrates motion, change, and appearance cues using a deep learning framework for robust moving object detection under challenging conditions. The proposed network consists of a two-stream encoder module followed by feature concatenation and a decoder module. Motion and change cues are computed through our tensor-based motion estimation and a multi-modal background subtraction modules. The proposed system was tested and evaluated on the change detection challenge datasets (CDnet-2014) and compared to state-of-the-art methods. On CDnet-2014 dataset, our approach reaches an average overall F-measure of 0.9852 and outperforms all current state-of-the-art methods. The network was also tested on the unseen SBI-2015 dataset and produced promising results.

Holistic Grid Fusion Based Stop Line Estimation

Runsheng Xu, Faezeh Tafazzoli, Li Zhang, Timo Rehfeld, Gunther Krehl, Arunava Seal

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Auto-TLDR; Fused Multi-Sensory Data for Stop Lines Detection in Intersection Scenarios

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Intersection scenarios provide the most complex traffic situations in Autonomous Driving and Driving Assistance Systems. Knowing where to stop in advance in an intersection is an essential parameter in controlling the longitudinal velocity of the vehicle. Most of the existing methods in literature solely use cameras to detect stop lines, which is typically not sufficient in terms of detection range. To address this issue, we propose a method that takes advantage of fused multi-sensory data including stereo camera and lidar as input and utilizes a carefully designed convolutional neural network architecture to detect stop lines. Our experiments show that the proposed approach can improve detection range compared to camera data alone, works under heavy occlusion without observing the ground markings explicitly, is able to predict stop lines for all lanes and allows detection at a distance up to 50 meters.

Automatic Semantic Segmentation of Structural Elements related to the Spinal Cord in the Lumbar Region by Using Convolutional Neural Networks

Jhon Jairo Sáenz Gamboa, Maria De La Iglesia-Vaya, Jon Ander Gómez

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Auto-TLDR; Semantic Segmentation of Lumbar Spine Using Convolutional Neural Networks

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This work addresses the problem of automatically segmenting the MR images corresponding to the lumbar spine. The purpose is to detect and delimit the different structural elements like vertebrae, intervertebral discs, nerves, blood vessels, etc. This task is known as semantic segmentation. The approach proposed in this work is based on convolutional neural networks whose output is a mask where each pixel from the input image is classified into one of the possible classes. Classes were defined by radiologists and correspond to structural elements and tissues. The proposed network architectures are variants of the U-Net. Several complementary blocks were used to define the variants: spatial attention models, deep supervision and multi-kernels at input, this last block type is based on the idea of inception. Those architectures which got the best results are described in this paper, and their results are discussed. Two of the proposed architectures outperform the standard U-Net used as baseline.

Planar 3D Transfer Learning for End to End Unimodal MRI Unbalanced Data Segmentation

Martin Kolarik, Radim Burget, Carlos M. Travieso-Gonzalez, Jan Kocica

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Auto-TLDR; Planar 3D Res-U-Net Network for Unbalanced 3D Image Segmentation using Fluid Attenuation Inversion Recover

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We present a novel approach of 2D to 3D transfer learning based on mapping pre-trained 2D convolutional neural network weights into planar 3D kernels. The method is validated by proposed planar 3D res-u-net network with encoder transferred from the 2D VGG-16 which is applied for a single-stage unbalanced 3D image data segmentation. In particular, we evaluate the method on the MICCAI 2016 MS lesion segmentation challenge dataset utilizing solely Fluid Attenuation Inversion Recover (FLAIR) sequence without brain extraction for training and inference to simulate real medical praxis. The planar 3D res-u-net network performed the best both in sensitivity and Dice score amongst end to end methods processing raw MRI scans and achieved comparable Dice score to a state-of-the-art unimodal not end to end approach. Complete source code was released under the open-source license and this paper is in compliance with the Machine learning Reproducibility Checklist. By implementing practical transfer learning for 3D data representation we were able to successfully segment heavily unbalanced data without selective sampling and achieved more reliable results using less training data in single modality. From medical perspective, the unimodal approach gives an advantage in real praxis as it does not require co-registration nor additional scanning time during examination. Although modern medical imaging methods capture high resolution 3D anatomy scans suitable for computer aided detection system processing, deployment of automatic systems for interpretation of radiology imaging is still rather theoretical in many medical areas. Our work aims to bridge the gap offering solution for partial research questions.

DA-RefineNet: Dual-Inputs Attention RefineNet for Whole Slide Image Segmentation

Ziqiang Li, Rentuo Tao, Qianrun Wu, Bin Li

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Auto-TLDR; DA-RefineNet: A dual-inputs attention network for whole slide image segmentation

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Automatic medical image segmentation techniques have wide applications for disease diagnosing, however, its much more challenging than natural optical image segmentation tasks due to the high-resolution of medical images and the corresponding huge computation cost. Sliding window was a commonly used technique for whole slide image (WSI) segmentation, however, for these methods that based on sliding window, the main drawback was lacking of global contextual information for supervision. In this paper, we proposed a dual-inputs attention network (denoted as DA-RefineNet) for WSI segmentation, where both local fine-grained information and global coarse information can be efficiently utilized. Sufficient comparative experiments were conducted to evaluate the effectiveness of the proposed method, the results proved that the proposed method can achieve better performance on WSI segmentation tasks compared to methods rely on single-input.